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GlycoProteomics

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DATABASES

  • Glyconnect https://glyconnect.expasy.org/ GlyConnect is a platform integrating sources of information to help characterise the molecular components of protein glycosylation
  • GlyDB N-Glycan Structure Annotation of Glycopeptides Using a Linearized Glycan Structure Database
  • GlycoFish http://betenbaugh.jhu.edu/GlycoFish A Database of Zebrafish N-linked Glycoproteins Identified Using SPEG Method Coupled with LC/MS
  • GlycoFly Drosoph  http://betenbaugh.jhu.edu/GlycoFly GlycoFly is a database for Drosophila N-linked glycoproteins identified using SPEG—MS techniques.
  • GlycoPAT http://www. VirtualGlycome.org/glycopat GlycoProteomics Analysis Toolbox
  • GlyProt http://www.glycosciences.de/glyprot/ GlyProt is a web-based tool that enables meaningful N-glycan conformations to be attached to all the spatially accessible potential N-glycosylation sites of a known three-dimensional (3D) protein structure.
  • GlycoSuiteDB http://www.glycosuite.com GlycoSuiteDB is a relational database that curates information from the scientific literature on glyco-protein derived glycan structures
  • O-GlycBase http://www.cbs.dtu.dk/databases/OGLYCBASE/ A database of glycoproteins with O-linked glycosylation sites
  • UniCarbKB http://unicarbkb.org UniCarbKB : New database features for integrating glycan structure abundance, compositional glycoproteomics data, and disease associations
  • UniPep http://www.unipep.org A database for human N-linked glycosites : a resource for biomarker discovery

PREDICTIONS
N-Glycosylation

  • I-GPA Integrated GlycoProteome Analyzer (I-GPA) for Automated Identification and Quantitation of Site-Specific N-Glycosylation.
  • MAGIC http://ms.iis.sinica.edu.tw/MAGIC-web/index.html. Identifies intact N-glycosylated peptides from a public protein database without requiring any prior information of proteins or glycans
  • NetNGlyc http://www.cbs.dtu.dk/services/NtNGlyc/ The NetNglyc server predicts N-Glycosylation sites in human proteins using artificial neural networks that examine the sequence context of Asn-Xaa-Ser/Thr sequons
  • GlycoProt

O-Glycosylation

  • DictyOGlyc http://www.cbs.dtu.dk/services/DictyOGlyc/ The DictyOGlyc server produces neural network predictions for GlcNAc. O-glycosylation sites in Dictyostelium discoideum proteins.
  • ISOGlyP isoglyp.utep.edu/ Provides isoform specific O-glycosylation prediction
  • NetOGlyc www.cbs.dtu.dk/services/NetOGlyc/ The NetOglyc server produces neural network predictions of mucin type GalNAc O-glycosylation sites in mammalian proteins.
  • O-GlcNAcPred http://121.42.167.206/OGlcPred/ A sensitive predictor to capture protein O-GlcNAcylation sites
  • YinOYang www.cbs.dtu.dk/services/YinOYang/ The YinOYang WWW server produces neural network predictions for O-ß-GlcNAc attachment sites in eukaryotic protein sequences.

N-O-Glycosylation

C-Mannosylation

Lysine Glycation

ANALYSIS

ANALYSIS MS