1er
novembre
2019
news

The core fucose on an IgG antibody is an endogenous ligand of Dectin-1

The core fucose is a significant modification of N-glycans and has profound implications in immune regulation....

25
octobre
2019
news

ProCarbDB : a database of carbohydrate-binding proteins

ProCarbD is a freely accessible, userfriendly database that comprises of 5242 true protein-carbohydrate...

6
octobre
2019
news

Mammalian Y RNAs are modified at discrete...

The article is the first report, ever, of the binding of N-glycans to RNA molecules. While studying the...

1er
octobre
2019
news

Structural Glycobiology in the Age of Electron Cryo-Microscopy

This is a very timely publication, as resolution revolution in electron cryo-microscopy (cryo-EM) which is now...

15
septembre
2019
news

Emerging Structural Insights into Glycosyltransferase-mediated Synthesis of Glycans

Glycans linked to proteins and lipids play key roles in biology. The accurate replication of cellular glycans...

11
septembre
2019
news

Electron Microdiffraction Reveals the Nanoscale Twist Geometry of Cellulose Nanocrystals

Crystalline cellulose fibrils, commonly called nanocellulose, are obtained from native cellulosic tissues....

31
août
2019
news

From Chitin to Chitosan

Two hundred years after its identification in mushrooms, and later in insects, chitin, and its derivative...

12
août
2019
news

The challenges of glycan recognition with natural and artificial receptors

Glycans – simple or complex carbohydrates – play key roles as recognition determinants and modulators of...

2
août
2019
news

Glycans in Drug Discovery

Glycosience is benefitting from the global progress in biophysical techniques. Those developments are...

25
juillet
2019
news

An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells

17
juillet
2019
news

Revisiting the Language of Glycoscience

12
juillet
2019
news

A Specific, Glycomimetic Langerin Ligand for Human Langerhans Cell Targeting

23
juin
2019
news

Hydroxyl Groups in Synthetic and Natural-Product-Derived Therapeutics :

By forming extended hydrogen-bond networks, the contribution of hydroxyl groups to affinity can reach several...

12
juin
2019
news

Reprogramming the Enzymatic Assembly Line for Site-specific Fucosylation

Fucosylated carbohydrate determinants are common components of cell surface glycoconjugates and secreted...

2
juin
2019
news

Dynamics of Membrane-Embedded Lipid-Linked Oligosaccharides for the Three Domains of Life

Lipid-linked oligosaccharides (LLOs) are the substrates of oligosaccharyltransferases (OSTs), enzymes that...

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