1er
juin
2023
news

Glycomimetics for the Inhibition and Modulation of Lectins

Carbohydrates play vital roles in how cells interact with each other and their environment. They help cells...

29
mai
2023
news

Computational Studies on Glycosaminoglycan Recognition of Sialyl Transferases

Despite decades of research, glycosaminoglycans (GAGs) have not been known to interact with sialyl...

24
mai
2023
news

Spatial Imaging of GlycoRNA in Single Cells with ARPLA

Little is known about the biological roles of glycosylated RNAs (glycoRNAs), a recently discovered class of...

18
mai
2023
news

GlycoDraw : A Python Implementation for Generating High-Quality Glycan Figures

The structural complexity of glycans is communicated through simplified and unified visual representations...

15
mai
2023
news

A Brief History of Visualizing Membrane Systems in Molecular Dynamics Simulations

Understanding lipid dynamics and function, from the level of single, isolated molecules to large assemblies,...

11
mai
2023
news

Can ChatGPT pass Glycobiology ?

Under « Can ChatGPT pass Glycobiology ? » the authors present and discuss a systematic evaluation of how ChatGPT...

12
avril
2023
news

Well-Defined Heparin Mimetics Can Inhibit Binding of the Trimeric Spike of SARS-CoV‑2 in a Length-Dependent Manner

SARS-CoV-2 employs heparan sulfate (HS) as an initial cellular attachment factor, and therefore, there is...

2
avril
2023
news

Anti-glycan monoclonal antibodies : Basic research and clinical applications

Anti-glycan monoclonal antibodies have essential applications in human health and basic research. Therapeutic...

29
mars
2023
news

Hyaluronan and Reactive Oxygen Species Signaling—Novel Cues from the Matrix ?

Hyaluronan (HA) is a naturally occurring non-sulfated glycosaminoglycan (GAG) localized to the cell surface...

13
mars
2023
news

Many Roles of Carbohydrates : A Computational Spotlight on the Coronavirus S Protein Binding

Glycosylation is one of the post-translational modifications, with more than 50% of human proteins being...

8
mars
2023
news

Designing Smaller, Synthetic, Functional Mimetics of Sulfated Glycosaminoglycans as Allosteric Modulators of Coagulation Factors

Glycosaminoglycans (GAGs) are arguably the most diverse collection of natural products. Unfortunately, this...

5
mars
2023
news

Glycosaminoglycans : What Remains to be Deciphered ?

Within the context of a European Cooperation in Science and Technology Action (INNOGLY), scientists of the...

1er
mars
2023
news

Biochemical and Structural Basis of Sialic acid Utilization by Gut Microbes

The human gastrointestinal (GI) tract harbours diverse microbial communities collectively known as the gut...

28
février
2023
news

Structural and Biochemical Insight into a Modular β-1,4-Galactan Synthase in Plants

Rhamnogalacturonan I (RGI) is a structurally complex pectic polysaccharide with a backbone of alternating...

26
février
2023
news

Tuning specificity and topology of lectins through synthetic biology

Lectins are non-immunoglobulin and non-catalytic glycan-binding proteins that are able to decipher the...

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