Glycomimetics for the Inhibition and Modulation of Lectins
Carbohydrates play vital roles in how cells interact with each other and their environment. They help cells...
Computational Studies on Glycosaminoglycan Recognition of Sialyl Transferases
Despite decades of research, glycosaminoglycans (GAGs) have not been known to interact with sialyl...
Spatial Imaging of GlycoRNA in Single Cells with ARPLA
Little is known about the biological roles of glycosylated RNAs (glycoRNAs), a recently discovered class of...
GlycoDraw : A Python Implementation for Generating High-Quality Glycan Figures
The structural complexity of glycans is communicated through simplified and unified visual representations...
A Brief History of Visualizing Membrane Systems in Molecular Dynamics Simulations
Understanding lipid dynamics and function, from the level of single, isolated molecules to large assemblies,...
Can ChatGPT pass Glycobiology ?
Under « Can ChatGPT pass Glycobiology ? » the authors present and discuss a systematic evaluation of how ChatGPT...
Well-Defined Heparin Mimetics Can Inhibit Binding of the Trimeric Spike of SARS-CoV‑2 in a Length-Dependent Manner
SARS-CoV-2 employs heparan sulfate (HS) as an initial cellular attachment factor, and therefore, there is...
Anti-glycan monoclonal antibodies : Basic research and clinical applications
Anti-glycan monoclonal antibodies have essential applications in human health and basic research. Therapeutic...
Hyaluronan and Reactive Oxygen Species Signaling—Novel Cues from the Matrix ?
Hyaluronan (HA) is a naturally occurring non-sulfated glycosaminoglycan (GAG) localized to the cell surface...
Many Roles of Carbohydrates : A Computational Spotlight on the Coronavirus S Protein Binding
Glycosylation is one of the post-translational modifications, with more than 50% of human proteins being...
Designing Smaller, Synthetic, Functional Mimetics of Sulfated Glycosaminoglycans as Allosteric Modulators of Coagulation Factors
Glycosaminoglycans (GAGs) are arguably the most diverse collection of natural products. Unfortunately, this...
Glycosaminoglycans : What Remains to be Deciphered ?
Within the context of a European Cooperation in Science and Technology Action (INNOGLY), scientists of the...
Biochemical and Structural Basis of Sialic acid Utilization by Gut Microbes
The human gastrointestinal (GI) tract harbours diverse microbial communities collectively known as the gut...
Structural and Biochemical Insight into a Modular β-1,4-Galactan Synthase in Plants
Rhamnogalacturonan I (RGI) is a structurally complex pectic polysaccharide with a backbone of alternating...
Tuning specificity and topology of lectins through synthetic biology
Lectins are non-immunoglobulin and non-catalytic glycan-binding proteins that are able to decipher the...
