25
mai
2021
news

Identifying the Origin of Local Flexibility in a Carbohydrate Polymer

Correlating the structures and properties of a polymer to its monomer sequence is key to understanding how its...

11
mai
2021
news

The clinical impact of glycobiology : targeting selectins, Siglecs and mammalian glycans

Advances in genomics, glycoproteomics and tools from chemical biology have made glycobiology more tractable...

3
mai
2021
news

Big-Data Glycomics : Tools to Connect Glycan Biosynthesis to Extracellular Communication

Characteristically, cells must sense and respond to environmental cues. Despite the importance of cell–cell...

25
avril
2021
news

Anti-Glycan Antibodies : Roles in Human Disease

Endogenous carbohydrate-binding antibodies that recognize bacterial, fungal, and other microbial carbohydrates...

5
avril
2021
news

Enhanced validation of small-molecule ligands and carbohydrates in the Protein Data Bank

The Worldwide Protein Data Bank (wwPDB) has provided validation reports based on recommendations from...

1er
avril
2021
news

Laboratory Observation of, Astrochemical Search for, and Structure of Elusive Erythrulose in the Interstellar Medium

Rotational spectroscopy provides the most powerful means of identifying molecules of biological interest in...

24
mars
2021
news

First Neutron 3D Structure of a Protein Interacting with a Fully Deuterated Carbohydrate Ligand

Carbohydrate-binding proteins from pathogenic bacteria and fungi participate in various pathological...

17
mars
2021
news

Cracking the « Sugar Code » : A Snapshot of N- and O-Glycosylation Pathways and Functions in Plants Cells.

Glycosylation is a fundamental co-translational and/or post-translational modification process. An attachment...

8
mars
2021
news

An Integrated Visualization for Lectin Microarray-based Mouse Tissue Glycome Mapping Data with Lectin Histochemistry

Laser microdissection-assisted lectin microarray provides quantitative and qualitative information on glycans...

10
février
2021
news

Developing Fibrillated Cellulose as a Sustainable Technological Material

Cellulose is the most abundant biopolymer on Earth, found in trees, waste from crops and other biomass. The...

1er
février
2021
news

Glycan Utilization Systems in the Human Gut Microbiota : a Gold Mine for Structural Discoveries

The complex glycans comprising ‘dietary fibre’ evade the limited repertoire of human digestive enzymes. They...

28
janvier
2021
news

Starch in the Bioeconomy

Starch is the most widespread and abundant reserve carbohydrate in plants and is unique in that it can be used...

20
janvier
2021
news

Towards a Unified Open-Access Dataset of Molecular Interactions

The International Molecular Exchange (IMEx) Consortium provides scientists with a single body of...

15
janvier
2021
news

Beyond Shielding : The Roles of Glycans in the SARS-CoV‑2 Spike Protein

The ongoing COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)....

12
décembre
2020
news

DeepMind’s program for determining the 3D shapes of proteins

DeepMind’s program, called AlphaFold, outperformed approximately 100 other teams in a biennial...

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