Glycans

2slides_pout_travelet_page_3.png

DATABASES

  • BioOligo http://glyco3d.cermav.cnrs.fr/search.php?type=bioligo As part of the suite of interlinked Databases of 3D Structures of Glycan, BioOligo. contains representations, 3D structures and NMR spectra of most occurring glycans
  • GlycoStore http://www.glycostore.org Provides a centralised resource that combines glycan structure information with chromatographic separation and electrophoretic data.
  • KEGG Glycan https://www.genome.jp/kegg/glycan/ The KEGG GLYCAN structure database is a collection of experimentally determined glycan structures. It contains all unique structures taken from CarbBank, structures entered from recent publications, and structures present in KEGG pathways
  • UniCarb-DB http://unicarb-db.expasy.org/ UniCarb-DB is a structural and mass spectrometric database used in glycomics. UniCarb-DB provides over 1000 LC-MS/MS spectra for N- and O-linked glycans released from glycoproteins that were manually annotated.

SEARCH

PREDICTIONS

ANALYSIS

  • Galaxy http://www.glycoanalysis.info/galaxy2/manual/User_Manual.pdfProvides a useful method for an analytical procedure for N-glycan structures. Galaxy is a 2D/3D mapping method developed for the structural determination of asparagine-linked oligosaccharides (N-glycans) in glycoproteins.
  • GIGTool https://www.genome.jp/tools/kcam/ GIG Tool is an application that extracts (i) precursor masses, (ii) oxonium ions and glycan fragments from tandem (liquid chromatography (LC)–MS/MS) mass spectra for glycan identification, and (iii) reporter ions from quaternary amine containing isobaric tag for glycan (QUANTITY) isobaric tags.
  • GLYCH GLYCH (GLYcan CHaraterization) is package for glycan characterization using MS/MS.
  • GlycoMod https://web.expasy.org/glycomod/ GlycoMod is a tool that can predict the possible oligosaccharide structures that occur on proteins from their experimentally determined masses
  • GlycoProfileAssigner http://glycananalyzer.neb.com Automated structural assignment with error estimation for glycan LC data
  • GlycoSearchMS http://www.glycosciences.de/database/start.php?action=form_ms_search GlycoSearchMS takes a list of mass spectra peak values as input and searches for matches with the calculated fragments of SweetDB structures.
  • GlycoWorkbench https://glycoworkbench.software.informer.com/2.1/ A suite of software tools designed for the rapid drawing of glycan structures and for assisting the process of structure determination from mass spectrometry data.
  • GRITS ToolBox www.grits-toolbox.org/ GRITS Toolbox combines the analytical power of glycan permethylation with glycopeptide analysis, preserving site-specific information for comprehensive glycoprotein analysis
  • KCaMhttps://www.genome.jp/tools/kcam/ KEGG Carbohydrate Matcher s a tool for the analysis of carbohydrate sugar chains, or glycans. It consists of a web-based graphical user interface that allows users to enter glycans easily with the mouse
  • MultiGlycan https://bio.tools/MultiGlycan To help user to gather glycan profile information from LC-MS Spectra. It also reports quantity of specific glycan composition