Introduction to Blood Group
The ABO(H) system although it is probably the oldest and most typed for human blood group system, yet from many
Lola Svensson, Serge Pérez & Stephen Henry
The ABO(H) system although it is probably the oldest and most typed for human blood group system, yet from many
The presence of a blood group A and B antigens on the outside of a red cell starts with the
The ABO gene was first cloned in 1990 and is located on the long arm of chromosome 9q34 Ferguson-Smith et al.,1976Yamamoto,
Glycosyltransferases are type II membrane proteins, with a short N-terminal cytoplasmic tail, a hydrophobic transmembrane region (TM) and the C-terminal
Synthesis of ABO antigens, like all carbohydrate antigens, is the result of a complex series of interactions between a range
The biosynthesis of the ABO and all its related precursors such as H, I and P blood group system glycolipids
The biosynthesis of glycoprotein based blood group A, B and H antigens relating to terminal glycosylation is similar to glycolipids
The ABH antigens of red cells are carried by both glycoproteins and glycolipids on a variety of “peripheral cores” that
In addition to those interactions with glycosyltransferases involved in biosynthesis described in previous chapters above (Figure 4), the effects of
Anti-ABO antibodiesA and -B antibodies are present in individuals lacking the specific ABO antigen.The principles described in this section of
Ando, S., et al., A novel pentaglycosyl ceramide containing di-beta-N-acetylgalactos-aminyl residue (Para-Forssman glycolipid) isolated from human erythrocyte membrane. Adv Exp Med Biol,
Lola Svensson Lola Svensson received her training as a biomedical scientist in Clinical Chemistry and Transfusion Medicine from the Univerisity