Close this search box.

Solid-State NMR Investigations of Extracellular Matrixes and Cell Walls of Algae, Bacteria, Fungi, and Plants


N. Ghassemi, A. Poulhazan, F. Deligey, F. Mentink-Vigier, I. Marcotte & T. Wang*


Chemical Reviews 2022, 122, 10, 10036-10086 DOI: 10.1021/acs.chemrev.1c00669

The review highlights the recent high-resolution investigations of intact ECMs and native cells in many organisms spanning plants, bacteria, fungi, and algae.
Extracellular matrixes (ECMs), such as the cell walls and biofilms, are essential for supporting cell integrity and function and regulating intercellular communication. These biomaterials are also of significant interest to the production of biofuels and the development of antimicrobial treatment. Solid-state nuclear magnetic resonance (ssNMR) and magic-angle spinning-dynamic nuclear polarization (MAS-DNP) are uniquely powerful for understanding the conformational structure, dynamical characteristics, and supramolecular assemblies of carbohydrates and other biomolecules in ECMs. The authors spotlight the structural principles identified in ECMs. They discuss the current technical limitation and underexplored biochemical topics. They point out the perspectives enabled by the recent advances of the rapidly evolving ssNMR technology.

Latest news

The Kuiper Belt object (KBO) Arrokoth orbits the Sun as part of the Kuiper belt...

The role of glycosaminoglycans (GAGs) in modulating bone morphogenetic protein (BMP) signaling is a relatively...

Glycans, due to their variable compositions and highly dynamic conformations, significantly enhance the diversity of...

Advances in simulation, combined with technological developments in high-performance computing, have made it possible to...