Introduction
A critical step in drug discovery is the identification of high-affinity ligands for specific macromolecular targets. This is why, over
Juan-Carlos Munoz-Garcia, Jesus Angulo Alvarez & Pedro Manuel Nieto Mesa
A critical step in drug discovery is the identification of high-affinity ligands for specific macromolecular targets. This is why, over
Assuming a protein receptor P with a single binding site for the ligand L, such that they interact to transiently
The theory of transferred NOE has been described in numerous publications (Balaram et al., 1972a) (Balaram et al 1972b) (
The STD NMR experiment (Mayer & Meyer, 1999) is another spectroscopic technique to study the interactions, in solution, between a large molecule
Juan Carlos Munoz Garcia After graduating as a Bachelor of Science in Chemistry from the University of Almería (Spain), Juan