Mammalian Y RNAs are modified at discrete...
The article is the first report, ever, of the binding of N-glycans to RNA molecules. While studying the glycosylation process, an unexpected molecule was spotted that turned out to be a sialylated N-glycan attached, via guanosine, to a subset of noncoding RNA molecules including small Y RNAs. The molecular complex, abbreviated as glycoRNAs, occurs in different cell types and mammalian species, both in cultured cells and in vivo.
RNA is normally found only in the nucleus and cytosol of cells, while glycosylation is thought to occur in the endoplasmic reticulum and Golgi bodies.
Confirmation of these results would certainly alter some face of biochemistry as we know, and suggest, among other, vast new roles for RNA !